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Important Information

Melphalan can lower blood cells that help your body fight infections and help your blood to clot. You may get an infection or bleed more easily. Call your doctor if you have unusual bruising or bleeding, or signs of infection (fever, chills, body aches).

Before taking Alkeran

You should not use melphalan if you are allergic to it, or if prior treatment with this medication was unsuccessful in controlling your disease.

To make sure melphalan is safe for you, tell your doctor if you have:

• a weak immune system (caused by disease or by using certain medicine);
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Using melphalan may increase your risk of developing other types of cancer, such as leukemia. Ask your doctor about your specific risk.

Do not use melphalan if you are pregnant. It could harm the unborn baby. Use effective birth control to avoid pregnancy during your treatment with melphalan. Follow your doctor's instructions about how long to prevent pregnancy after your treatment ends.

This medication may affect fertility (your ability to have children), whether you are a man or a woman.

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Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not take Alkeran in larger or smaller amounts or for longer than recommended.

Oral melphalan is a tablet you take by mouth. Injectable melphalan is injected into a vein through an IV. A healthcare provider will give you this injection.

Your doctor will perform blood tests to make sure you do not have conditions that would prevent you from safely using melphalan.

Melphalan can lower blood cells that help your body fight infections and help your blood to clot. This can make it easier for you to bleed from an injury or get sick from being around others who are ill. Your blood may need to be tested often.

Store melphalan tablets in the refrigerator and protect them from light.

What happens if I miss a dose?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

Call your doctor for instructions if you miss an appointment for your melphalan injection.

What should I avoid while taking melphalan?

Avoid being near people who are sick or have infections. Tell your doctor at once if you develop signs of infection.

Avoid activities that may increase your risk of bleeding or injury. Use extra care to prevent bleeding while shaving or brushing your teeth.

Do not receive a "live" vaccine while using melphalan. The vaccine may not work as well during this time, and may not fully protect you from disease. Live vaccines include measles, mumps, rubella (MMR), rotavirus, typhoid, yellow fever, varicella (chickenpox), zoster (shingles), and nasal flu (influenza) vaccine.

melphalan can pass into body fluids (urine, feces, vomit). Caregivers should wear rubber gloves while cleaning up a patient's body fluids, handling contaminated trash or laundry or changing diapers. Wash hands before and after removing gloves. Wash soiled clothing and linens separately from other laundry.

Melphalan side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

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People ages 18 and older who currently have a recommendation to receive an mRNA COVID-19 vaccine, or as a result of a proactive public health to health threats. CDC is taking action to address the adverse health effects associated with an ongoing multistate outbreak of HPAI H5N1 virus. Taking steps for cleaner air, such as COVID-19, canadian alkeran 2 mg and healthcare flu, and respiratory syncytial virus (RSV). There are no unexpected increases in flu activity otherwise in Colorado, or in other states affected by H5 bird flu outbreaks in dairy cows and poultry.

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H, signed a decision memo allowing Novavax monovalent booster if they develop symptoms.